The expression of tenascin-C and tenascin-W in human ossicles
نویسندگان
چکیده
منابع مشابه
Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumors
BACKGROUND Tenascins are large glycoproteins found in the extracellular matrix of many embryonic and adult tissues. Tenascin-C is a well-studied biomarker known for its high overexpression in the stroma of most solid cancers. Tenascin-W, the least studied member of the family, is highly expressed in the stroma of colon and breast tumors and in gliomas, but not in the corresponding normal tissue...
متن کاملEctopic expression of tenascin-C.
We read, with much interest, the recent Research Article by Järvinen et al. (Järvinen et al., 2003), in which the authors show that, after removing the cast from an immobilized rat hind leg, within 8 weeks tenascin-C (TN-C) expression is increased in tendon and the myotendinous junction, but there is no de novo appearance of TN-C in skeletal muscle connective tissue. The authors extensively cri...
متن کاملTenascin-C expression in normal, inflamed, and scarred human corneas.
AIMS/BACKGROUND In adult tissues the expression of tenascin-cytotactin (TN-C), an extracellular matrix glycoprotein, is limited to tumours and regions of continuous renewal. It is also transiently expressed in cutaneous and corneal wound healing. There are limited data regarding its expression in inflammation and scarring of the adult human cornea. In this study, TN-C expression patterns in nor...
متن کاملThe Adhesion Modulating Properties of Tenascin-W
Tenascins are extracellular matrix glycoproteins associated with cell motility, proliferation and differentiation. Tenascin-C inhibits cell spreading by binding to fibronectin; tenascin-R and tenascin-X also have anti-adhesive properties in vitro. Here we have studied the adhesion modulating properties of the most recently characterized tenascin, tenascin-W. C2C12 cells, a murine myoblast cell ...
متن کاملTenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration.
The whisker follicle has CD34-positive stem cells that migrate from their niche near the bulge along the glassy membrane to the whisker bulb, where they participate in the formation of the whisker shaft. Using immunohistochemistry, we found the glycoprotein tenascin-C in the fibrous capsule of mouse whisker follicles, along the glassy membrane and in the trabecular region surrounding keratin-15...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Anatomy
سال: 2016
ISSN: 0021-8782
DOI: 10.1111/joa.12496